A tunable refractive index matching medium for live imaging cells, tissues and model organisms
نویسندگان
چکیده
منابع مشابه
A tunable refractive index matching medium for live imaging cells, tissues and model organisms
In light microscopy, refractive index mismatches between media and sample cause spherical aberrations that often limit penetration depth and resolution. Optical clearing techniques can alleviate these mismatches, but they are so far limited to fixed samples. We present Iodixanol as a non-toxic medium supplement that allows refractive index matching in live specimens and thus substantially impro...
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ژورنال
عنوان ژورنال: eLife
سال: 2017
ISSN: 2050-084X
DOI: 10.7554/elife.27240